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Beta Bionics iLet


The iLet is an automated insulin delivery system that reduces the need to make decisions about your diabetes management – because it makes the decisions for you.

Additional Details

Go Bionic with the iLet Bionic Pancreas.
No more:
Carb Counting*
Carb Ratios
Correction Factors
Pre Set Basal Rates
Or any of the other settings that might be overwhelming about other insulin delivery devices
The Ilet needs only one number- your weight.
*User must be carb aware

Safety Information


* CGM sold separately.

† If glucose values are predicted to be above 180 mg/dL, Control-IQ technology calculates a correction bolus using the Personal Profile settings and a target of 110 mg/dL and delivers 60% of that value.

‡ Bolus delivery from the t:connect mobile app requires a compatible smartphone model and operating system, an app update, a remote software update on the t:slim X2 insulin pump and additional training. Only available to customers who reside in the United States.

◇ Tandem Diabetes Care has compensation agreements with Mark Andrews, Lauren Salko, and Ben Tzeel.


1. #1 rating claim based on dQ&A US Q2 2023 (Apr-Jun 2023) Diabetes Connections Patient Panel Report. $0 out of pocket claim based on direct orders from Tandem customers with commercial insurance from 1/1/2022-12/31/2022. Data on file. Actual cost may vary and is subject to individual insurance coverage.

2. Brown SA, Kovatchev BP, Raghinaru D, et al. Six-month randomized, multicenter trial of closed-loop control in type 1 diabetes. N Engl J Med. 2019;381(18):1701-1717. doi: 10.1056/NEJMoa1907863.

3. Kudva YC, Laffel LM, Brown SA, et al. Patient-Reported Outcomes in a Randomized Trial of Closed-Loop Control: The Pivotal International Diabetes Closed-Loop Trial. Diabetes Technol Ther. 2021;23(10):673-683. doi: 10.1089/dia.2021.0089

Important Safety Information

Frequently Asked Questions

Which Continuous Glucose Monitors are compatible with my Beta Bionics iLet Bionic Pancreas

The Dexcom G6 and G7

Is the Beta Bionics iLet Bionic Pancreas for children?

The device is indicated for use by people with type 1 diabetes 6 years of age and older.

Is my iLet water proof?

The device is protected up to 12 feet of water for up to 30 minutes

How can I best succeed while using the iLet?

The iLet is different from any other insulin delivery device, as you cannot program any insulin settings or control any of the insulin dosing. The iLet can take a few days to learn how to best take care of your diabetes. The iLet will work best if you let it do the work for you. We recommend that you avoid overthinking what the iLet is doing.

Will I have to treat low blood glucose levels with the iLet?

Yes. You may still have low blood glucose levels (hypoglycemia) that you will need to treat with fast- acting sugar. The iLet will reduce or stop insulin dosing automatically in response to low CGM levels. You will still need to treat low blood glucose levels while using the iLet.

Do I need to correct high blood glucose levels with the iLet?

No. You cannot give additional insulin boluses when your blood glucose levels are high (hyperglycemia). The iLet automatically tries to give you insulin to bring your blood glucose down (this may take longer than you expect). You may need to change your infusion set or tubing and cartridge if you think your high blood glucose levels could be due to a problem with your insulin, tubing, or set. When in doubt, change it out!

How do I take insulin for meals?

When you eat meals, you should enter a Meal Announcement into the iLet. There is no need to count carbohydrates, and the iLet does not use a carbohydrate-to-insulin ratio. Instead, you tell the iLet if the amount of carbs you are eating is Usual for you, More than usual, or Less than usual. The iLet will use this information to determine how much insulin to give you. You cannot choose the exact dose of insulin (this has made some people uncomfortable in clinical studies).

What happens if I do not announce my meals?

The iLet will automatically give you insulin as your blood glucose rises, but it will not be able to track and learn from your meals. Your blood glucose may go higher and stay higher for longer than if you had announced the meal. 

CAUTION: This may lead to hypoglycemia later due to the correction algorithm adding more insulin than it would have if you had announced the meal.

What if I forget to announce a meal?

You can announce a meal up to 30 minutes after you start eating. If you forget to announce your meal, and more than 30 minutes have passed since you started eating, do not announce the meal. If you forget to announce your meal, the iLet will automatically deliver insulin in response to your rising CGM levels. Your blood glucose levels may go higher and stay higher for longer than if you had used the Meal Announcement feature. Having a low blood glucose later is also more likely.

CAUTION: After 30 minutes your glucose is already rising and the iLet has already dosed insulin according to your rising CGM levels, even without a meal announcement. If you announce a meal during this time, you will “stack” insulin and be at risk for severe hypoglycemia. This will also confuse the iLet, causing future meal doses to be less effective.

I ate or drank carbohydrates to treat a low blood glucose. Should I announce those carbohydrates as a meal?

No. Do not announce a meal for carbohydrates used to treat low blood glucose.

CAUTION: This could cause additional hypoglycemia and is dangerous.

Can I change how much insulin the iLet is giving me?

No. You cannot change insulin doses with the iLet. All insulin doses are automatically calculated by three separate algorithms which are continuously learning. The only action you can take to influence insulin delivery is to issue a Meal Announcement before eating a meal, or to disconnect from the iLet temporarily. Blood glucose control will worsen if you try to trick the system

I usually have a snack before bed to keep my blood sugar in range overnight. Do I need to do this while using the iLet? If so, should I announce my bedtime snack?

You do not need to eat a bedtime snack to keep your blood glucose in range overnight while using the iLet. If you chose to eat before bed, you should announce it to the iLet the same as you would during the day. This will give you insulin upfront and help prevent additional dosing in response to the rise in glucose after you eat. This will reduce the risk of hypoglycemia during the night.

I do not eat foods with carbohydrates and if I do, they are very low carb. Should I still announce my meals?

No. If you eat a very low carb diet or no carbs at all, you should not announce meals. 

Can I use the meal announcement to bring my glucose level down if I am not eating?

No. This can be dangerous. 

CAUTION: It could lead to severe hypoglycemia and confuse the iLet, causing future meal doses to be less effective.

 If my glucose is high and I am about to eat, should I announce a meal that is larger than my actual meal to get more insulin correction up front?

No. Do not announce a meal that is larger than the actual meal size to correct high glucose levels. The iLet will have already delivered correction insulin in response to your high glucose. 

CAUTION: Announcing a larger meal than the actual size could lead to severe hypoglycemia and confuse the iLet, causing future meal doses to be less effective.

I am used to counting carbohydrates. I saw how much insulin the iLet gave me for my last meal. Should I work backwards to figure out my meal size based on my old insulin-to- carbohydrate ratio? 

No. The iLet does not use insulin to carbohydrate ratios to dose insulin for meals. Do not calculate the amount of carbohydrates you need based on the insulin dose your iLet gave you. This will affect the iLet’s ability to learn about your insulin needs and confuse the iLet, causing future meal doses to be less effective.

I think the iLet has not learned my meal dose(s) because my glucose is high after meal(s). Is there anything I can do?

You may need to take a few days and focus on helping the iLet learn about your meals. Be consistent with how you decide the meal type and size. 

  • Only select Breakfast if you are eating your breakfast, Lunch for your lunch, and Dinner for your dinner. 
  • Only think about the carbs in your meal when selecting the size, not the amount of fat or protein. 

Try to eat meals that have carbs in the Usual for me range and wait at least 4 hours before eating and announcing again.

 After a few days, your meal dose(s) should adapt. Refer to the Meal Announcement Guide for more information on meal announcements and helping the iLet adapt.

Still have more questions?

Please contact our office and one of our experts will assist you or visit the manufactures website for more information.